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PTH 1-34 ELISA Kit
名称 PTH 1-34 ELISA Kit
型号
报价 1
特点 PTH 1-34 ELISA Kit is intended for research use only in the qualitative detection of antibodies to human PTH (1-34) in humans or other animal models.}
  • 详细内容

一.产品名称:

通用名称:甲状旁腺激素1-34 ELISA试剂盒

英文名称:PTH 1-34 ELISA Kit

二.PTH 1-34 ELISA Kit介绍:

Teriparatide (rhPTH 1-34) is a recombinant human parathyroid hormone derivative consisting of the first 34 amino acids of the hormone. Teriparatide was approved as a drug by the FDA in 2002 and is sold by Eli Lilly & Co. under the brand name Forteo. Teriparatide is indicated for use in patients with osteoporosis. It is currently administered by injection and has an anabolic effect on bone, binding to the PTH/PTHrp Type 1 receptor with the same affinity as the intact molecule, PTH (1-84). This receptor activation results in a series of events leading to the ion of new trabecular and cortical bone. Research is continuing at pharmaceutical and biotech companies to pursue similar drugs and delivery pathways.
Immunogenicity for this drug, defined as the presence of antibodies to human PTH (1-34), was detected in 2.8% of women receiving teriparatide during the clinical trials of Forteo. The detection of these
circulating antibodies may be of clinical relevance for the proper assessment of patients.

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